Liverpool were dealt a devastating punch when midfielder Jordan Henderson hobbled off the pitch in an international game for the Three Lions of England.
The Englishman has been ruled out for fitness and is expected to sit out on plenty of games.
Klopp’s side will painfully deal with the unfortunate incident and slot in a replacement until he’s reached full recovery.
Klopp has enough options to explore in their midfield berth, despite his club’s loss.
But the Reds will further bleed as their Under-23 side were left dazed when defensive midfielder Matty Virtue went over on his ankle, damning his ankle ligament in the process.
Virtue skippered the side to a 3-1 victory over Leicester City until the sour incident that left the club’s holding their breath, wide-eyed with shock, when he was trimmed from the whole action late on in the game.
Virtue is the leading scorer in the competition, scoring six goals in ten PL2 games so far.
Virtue will be out for an extended period according to manager Neil Critchley, which has been echoed by the club.
Critchley made a pithy statement over their loss and just when he was he showing a willed and determined posture on the field of play, he got the knock, remarked Critchley.